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Berberine treatment inhibits cell proliferation and upregulates miRNA-22-3p expression in HepG2 cells. A: HepG2 cells were stimulated with 0-200 μM berberine for 0-48 h. Inhibition of cell proliferation by berberine was measured with an MTT assay. B: HepG2 cells stimulated with 100 μM berberine for up to 48 h compared with the untreated control. miRNA-22-3p expression was measured with qRT-PCR and is expressed as fold increases.
