FIG 1.
Genomic structures of recombinant HSVs. The schematics show representations of the genomes of the recombinant viruses used in this study. UL, unique long segment; US, unique short segment; CMVp, human cytomegalovirus immediate early (IE) promoter; scEGFR, anti-EGFR scFv-fused gD; scEpCAM, anti-EpCAM scFv-fused gD; NT, D285N/A549T mutations in gB that increase the rate of virus entry (38); Bh, R858H mutation in gB; Kt, A40T mutation in gK. Closed boxes show terminal and internal inverted repeats.