Table 2.
Protein | Group | p value | |||
---|---|---|---|---|---|
N0 IOD (mean) |
N1 IOD (mean) |
Nodal metastatic IOD (mean) |
|||
N0 versus N1 | N1 versus nodal | ||||
MMP-1 | 15,500 | 20,200 | 16,600 | ||
MMP-3 | 22,300 | 28,600 | 22,200 | <0.05 | <0.05 |
MMP-9 | 11,600 | 13,200 | 20,900 | <0.05 | |
TIMP-1 | 10,600 | 12,300 | 17,800 | ||
UPA | 26,000 | 37,600 | 39,400 | <0.05 | |
UPAR | 19,800 | 20,000 | 21,800 | ||
PAI-1 | 25,100 | 19,200 | 18,000 |
Semiquantitation of the signal was performed using ImageJ software and statistical significance acquired by applying the Mann–Whitney U test p < 0.05. N0 = without metastasis in ganglia nodes. N1 = with at least one metastatic ganglia node.