Figure 8. P. aeruginosa induces MCT-dependent elevation of lactate and ASL acidification in CFBE.

(A) CF HBE ASL pH and G. ASL Lactate concentration after 6 hours in HCO₃⁻-buffered basolateral salt solution containing 5 mM D-glucose in the absence (CF HBE only) or presence of 1 × 10⁶ CFU apical PA01 (+PA01), or 100 nM MCT2 inhibitor AR-C155858 (ARC). *P < 0.05, **P < 0.01, n = 5. Data represent the means ± S.E.M.