Table 2. Performance evaluation of different single incidence assays and multiassay algorithms (MAAs), Kisumu Incidence Cohort Study (KICoS): 2007–2009.
Assay/MAA | Recent, n (%) | w (95%CI) | Incidence-% (95% CI) |
---|---|---|---|
BED, n = 125 | |||
BED only | 19 (15.2) | 300 (270–329) | 2.53 (1.35–3.71) |
BED + VL | 16 (12.8) | 300 (270–329) | 2.13 (1.05–3.20) |
BED + LAg + VL* | 11 (8.8) | 300 (270–329) | 1.46 (0.58–2.35) |
LAg, n = 128 | |||
LAg only | 17 (13.2) | 184 (161–208) | 3.60 (1.81–5.39) |
LAg + VL | 16 (12.5) | 184 (161–208) | 3.39 (1.65–5.12) |
Biorad, n = 125 | |||
Biorad only | 25 (20.0) | 293 (263–323) | 3.40 (2.00–4.81) |
Biorad + VL | 23 (18.4) | 293 (263–323) | 3.13 (1.79–4.48) |
Note: Number of persons in the survey = 1106, persons HIV negative = 973, persons HIV positive = 133. BED, BED-CEIA OD-n < 0.8; LAg, LAg avidity OD-n < 1.5; Biorad, Biorad avidity AI < 30%; VL, viral load > 1000 copies/mL; w, mean duration of recency in days; CI, confidence intervals. *selected MAA.