Table 2. Testosterone, finasteride, SRE phytosterols and SRE fatty acids binding energies (kcal/mol) obtained with PyRosetta, using 5BR as a target protein.

Substrates	Unproductive position	Productive position
Testosterone	−7	−11
Finasteride	−6	−27
β-sitosterol	−2	−28
Stigmasterol	0.1	−29
Campesterol	0.5	−8
Daucosterol	−34	−30
Oleic acid	−12	−34
Lauric acid	−3	Not binding
Myristic acid	−8	−20
Palmitic acid	−12	−13
Linoleic acid	−7	−28