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. 2016 Nov 29;6:37427. doi: 10.1038/srep37427

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) 1 × 10⁶ cells were seeded into each piece of ICC scaffold and cell viability measured one day after cell seeding was used as the indicator of cell loading efficiency. (b) Cell viability was measured on days 1, 4, 7, 10, and 14 with the CCK-8 kit and proliferation was presented as the percentage of cell viability over day-1 value. The results are mean ± SD (N = 3). ***p < 0.001 compared with the bare ICC group; ^##p < 0.01 compared with the collagen group; ^###p < 0.001 compared with the collagen group.