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. 2016 Nov 29;6:37427. doi: 10.1038/srep37427

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Quantitative real-time PCR analysis of the mRNA of specific genes was conducted, and the data were normalized to the housekeeping gene GAPDH. The results are presented as the fold change in the day 1 value of each respective group (mean ± SD, N = 3). Fold change comparison between the collagen-functionalized ICC and bare ICC groups: *p < 0.05; **p < 0.01; ***p < 0.001. Comparison of the fibronectin-functionalized ICC and collagen-functionalized ICC groups: ^#p < 0.05; ^##p < 0.01; ^###p < 0.001.