Table 1. Clinical characteristic of study subjects in this study.
| Discovery stage |
Replication stage |
|||
|---|---|---|---|---|
| Paired tumor-normal | Only tumor tissuesb | Paired tumor-normal tissues | Healthy Women | |
| No. of samples | 85 | 830 | 50 | 23 |
| Age (yr ± s.d.) | 57.2 ± 15.4 | 58.4 ± 12.9 | 51.7 ± 10.9 | 52.0 ± 11.3 |
| Ethnicity | ||||
| White | 79 (92.9%) | 588 (70.8%) | 39 (78%) | 18 (78%) |
| Asian | 1 (1.2%) | 56 (6.8%) | 0 | 0 |
| Black | 5 (5.9%) | 79 (9.5%) | 11 (22%) | 5 (22%) |
| Unknown | 0 | 107 (12.9%) | 0 | 0 |
| ER status | ||||
| ER+ | 67 (78.9%) | 597 (71.9%) | 40 (80%) | NA |
| ER− | 15 (17.6%) | 181 (21.8%) | 10 (20%) | NA |
| Unknown | 3 (3.5%) | 52 (6.3%) | 0 | NA |
| Stage | ||||
| 0-I | 16 (18.8%) | 135 (16.2%) | 2 (4%) | NA |
| II | 46 (54.1%) | 469 (56.5%) | 14 (28%) | NA |
| III | 20 (23.5%) | 179 (21.6%) | 6 (12%) | NA |
| IV | 2 (2.4%) | 13 (1.6%) | 1 (2%) | NA |
| Unknown | 1 (1.2%) | 34 (4.1%) | 27 (54%) | NA |
aBRCA (breast invasive carcinoma) with matched adjacent normal tissues.
bBRCA without matched adjacent normal tissues.