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. 2016 Nov 29;6:38115. doi: 10.1038/srep38115

Figure 1. Effects of SM934 on disease progression in CIA mice.

Figure 1

(A) Timetable of CIA induction and treatment strategy in CII-immunized DBA/1J mice. All mice were sacrificed on day 40 post administration. (B) Arthritis severity scores of CIA development in CIA mice were recorded every two days after administration. Values are the mean ± SEM (n = 8). *P < 0.05, **P < 0.01 and ***P < 0.001 compared with the saline-treated CIA mice (saline). (C) Representative photographs of showing the gross features of left hind paws at day 14.