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. 2016 Nov 29;6:38115. doi: 10.1038/srep38115

Figure 2. Micro-CT analysis confirmed the efficacy of SM934 in CIA mice.

Figure 2

(A) Representative three-dimensional reconstruction of right hind paw of normal control mice and CIA mice treated with saline or SM934, respectively. (B) Histomorphometric analysis of the distal tibia for each treatment group, showing the values of four parameters including bone volume/total volume (BV/TV), trabecular number (Tb. N.), trabecular thickness (Tb. Th.), and trabecular spacing (Tb. Sp.) of mice control mice and CIA mice treated with saline or SM934. Values are the mean ± SEM (n = 8). *P < 0.05 compared with the saline-treated CIA mice (saline).