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. 2016 Nov 7;7(11):95. doi: 10.3390/genes7110095

Table 4.

Cis-acting expression of quantitative locus (cis-eQTL) analysis.

SNPs Target gene Cerebellar Cortex Frontal Cortex Temporal Cortex Occipital Cortex Putamen Thalamus Hippo-Campus Substantia Nigra Intralobular White Matter Medulla
rs10958725 CHRNB3 0.015 0.026
rs10958725 CHRNA6 0.042 0.027
rs10958726 CHRNB3 0.020 0.028
rs10958726 CHRNA6 0.043 0.031
rs13273442 CHRNB3 0.022 0.030
rs13273442 CHRNA6 0.043 0.032
rs4736835 CHRNB3 0.022 0.030
rs4736835 CHRNA6 0.043 0.032
rs1955186 CHRNB3 0.022 0.030
rs1955186 CHRNA6 0.043 0.032
rs1955185 CHRNB3 0.022 0.030
rs1955185 CHRNA6 0.043 0.032
rs13277254 CHRNB3 0.021 0.031
rs13277254 CHRNA6 0.042 0.033
rs13277524 CHRNB3 0.022 0.030
rs13277524 CHRNA6 0.043 0.032
rs6474412 CHRNB3 0.022 0.030
rs6474412 CHRNA6 0.043 0.032
rs6474413 CHRNB3 0.022 0.030
rs6474413 CHRNA6 0.043 0.032
rs7004381 CHRNB3 0.022 0.030
rs7004381 CHRNA6 0.043 0.032
rs4950 CHRNB3 0.022 0.030
rs4950 CHRNA6 0.043 0.032
rs13280604 CHRNB3 0.022 0.030
rs13280604 CHRNA6 0.043 0.032
rs16969968 CHRNA5 0.034 2.0 × 10−4 9.3 × 10−5 5.1 × 10−6 1.9 × 10−3 2.2 × 10−3 5.9 × 10−5 1.8 × 10−5 0.016 1.6 × 10−4
rs16969968 CHRNA3 8.9 × 10−4
rs1051730 CHRNA5 0.034 2.0 × 10−4 9.3 × 10−5 5.1 × 10−6 1.9 × 10−3 2.2 × 10−3 5.9 × 10−5 1.8 × 10−5 0.016 1.6 × 10−4
rs1051730 CHRNA3 8.9 × 10−4
rs6495308 CHRNA5 5.1 × 10−3 1.9 × 10−4 4.2 × 10−3 8.4 × 10−3 2.8 × 10−4 1.6 × 10−4 7.3 × 10−3 3.4 × 10−3
rs6495308 CHRNA3 2.7 × 10−3 0.013
rs6495308 CHRNB4 0.025 0.014
rs2236196 CHRNA4 0.044 0.035

α = 2.8 × 10−4 = 0.05/(10 brain tissues × 6 genes × 3 haplotype blocks); n = 134.