Table 3.
Selected studies on the association between HHV-8 and sarcoidosis
| First author/Year (Ref.) | Country | Molecular technique | Patients | Controls | OR (95% CI) |
|---|---|---|---|---|---|
| n/N | n/N | ||||
| Knoell, 2005 [60] | USA | PCR for HHV-8 DNA | 0/8 | 0/8 | - |
| Gazouli, 2002 [22] | Greece | PCR for HHV-8 DNA | 0/46 | 0/20 | - |
| Fredricks, 2002 [61] | USA | PCR for HHV-8 ORF 26 DNA | 0/18 | 0/4 | - |
| Maeda, 2000 [62] | Japan | Hemi-nested PCR for HHV-8 DNA | 4/119 | 4/120 | 1.01 (0.25–4.13) |
| Sugaya, 1999 [63] | Japan | Nested PCR for HHV-8 ORF 26 DNA | 0/12 | 1/1 | 0.01 (0.00–0.95) |
| Bélec, 1998 [64] | France | Nested PCR for HHV-8 ORF 25/26 DNA | 0/14 | 2/17 | 0.21 (0.01–4.84) |
| Di Alberti, 1997 [40] | Italy | Nested PCR for HHV-8 ORF 26 DNA and Heminested PCR for HHV-8 ORF 25 DNA | 38/39 | 6/113 | 677.67 (79.01–5812.52) |
HHV-8 Human Herpesvirus 8, ORF 25/26 DNA insertion sequence to identify HHV-8