Fig. 9.

Schematic representation of the study. This study suggests a possible mechanism to augment the immunological response on use of Riboflavin with antibiotics, AZM and CIP, which is achieved by enhanced ROS, ensuring enhancement of pathogen clearance and by the antioxidant properties of Riboflavin protection of the host cell is ensured, thus helped in maintaining a balanced redox state in the cell. Riboflavin by its proteasome inhibitory action might down regulates the NF-κβ pathway, thus reducing pro-inflammatory cytokines, nitric oxide and COX2, which on one hand prevent infection and on other hand lowers inflammatory damage