Multimodality MRI slices showing different preprocessing steps: (a) original T1, (b) original T2, (c) original FLAIR, (e) T1 after realign, unwarp, and bias field correction, (f) T2 after realign, unwarp, co-registration with T1 and biasfield correction, (g) FLAIR after realign, unwarp, co-registration with T1 and bias field correction, (h) intensity normalized T1, (i) intensity normalized T2, and (j) intensity normalized FLAIR.