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. 2016 Nov 17;8(11):311. doi: 10.3390/v8110311

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© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of Griffithsin (GRFT) on the secretion of some mediators of the immune response. Supernatants were collected from mouse peripheral blood mononuclear cell (mPBMC) cultures treated with 1 and 4 μM GRFT (horizontal and vertical lines, respectively), 0.37 and 1 μM Concanavalin A (ConA; grey and black, respectively) and phosphate-buffered saline (PBS; white) for 24, 48, and 72 h. Interleukin (IL) 1 beta (1b) (A); IL 6 (B); IL 10 (C); and tumor necrosis factor alpha (TNF-α) (D) amounts in the supernatants were assessed by enzyme-linked immunosorbent assay (ELISA).