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. 2016 Nov 19;8(11):345. doi: 10.3390/toxins8110345

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© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of apicidin (+/− DON) on TEER and viability of differentiated IPEC-J2. Differentiated IPEC-J2 were treated with (a) apicidin (0.438–2.5 µM) or (b) a combination of apicidin (0.438 µM) and DON (1.5 or 3 µM). TEER was measured after 24, 48 and 72 h. After the final TEER measurement, viability was determined via the NR assay. Asterisks indicate significant differences compared to control of the respective time point (* p < 0.05, ** p < 0.01, *** p < 0.001). Data represent mean ± SD, n = 3.