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. 2016 Oct 31;39(4):589–599. doi: 10.1590/1678-4685-GMB-2015-0295

Table 2. Metabolic pathways and gene ontologies for genes represented in the gene network.

Gene ontologies
Gene Metabolic pathway Cellular component Molecular function Biological process
CHD8 WNT signaling pathway Nuclear lumen Histone and DNA binding Embryo development
CSRP3 Cytoskeleton Contractile fiber Muscle organ development/Muscle structure development/Muscle system process
EID2B Nucleus Muscle differentiation Muscle organ development
HIF1AN Nucleus/cytosol Protein binding Muscle organ development/Muscle structure development
IKBKB MAPK signaling pathway Nucleus/cytosol Protein binding Muscle system process/Musculoskeletal movement/Skeletal muscle contraction
LEF1 WNT signaling pathway Nucleus Chromatin and DNA binding Embryo development
MAP2K1 MAPK signaling pathway Cytoskeleton/cytosol/nucleus Protein kinase activity Muscle system process
MRAS MAPK signaling pathway Intracellular GTPase activity/nucleotide binding Muscle organ development/Organ development
MYOG Nucleus Chromatin and DNA binding Muscle organ development/Muscle structure development
RBM24 Nucleus/cytoplasm Nucleotide binding Muscle organ development/Organ development
RSPO3 Extracellular region Receptor binding Embryo development
SOX7 Nucleus/cytoplasm Nucleic acid binding Embryo development
SUFU Hedgehog signaling pathway Nucleus/cytoplasm Transcription corepressor activity Embryo development/Organ development