Table 7. Influence of IL-6 –174 G/C polymorphism (SNP rs1800795) on the postprandial lipid profile before and after supplementation with pequi oil.
IL-6 genotypes | Total cholesterol (mg/dL) | Triglycerides (mg/dL) | HDL (mg/dL) | LDL (mg/dL) | VLDL (mg/dL) | |||||
---|---|---|---|---|---|---|---|---|---|---|
Before | After | Before | After | Before | After | Before | After | Before | After | |
GG | 187.37 ± 37.43 | 186.04 ± 35.98 | 116.06 ± 66.43 | 116.72 ± 55.42 | 54.02 ± 13.90 | 53.07 ± 13.80 | 109.68 ± 28.56 | 108.85 ± 27.77 | 23.21 ± 13.29 | 23.34 ± 11.08 |
GC | 193.22 ± 39.60 | 193.29 ± 33.71 | 111.35 ± 55.53 | 116.41 ± 46.27 | 55.14 ± 12.87 | 55.98 ± 13.32 | 116.19 ± 35.36 | 113.91 ± 29.26 | 22.27 ± 11.11 | 23.28 ± 9.25 |
CC | 169.57 ± 35.67 | 170.21 ± 32.63 | 108.21 ± 58.52 | 130.86 ± 63.45 | 51.93 ± 12.99 | 54.50 ± 16.22 | 96.00 ± 26.19 | 89.54 ± 21.75a,b | 21.64 ± 11.70 | 26.17 ± 12.69 |
p | 0.126 | 0.086 | 0.945 | 0.747 | 0.368 | 0.313 | 0.149 | 0.012 | 0.945 | 0.747 |
The data are expressed as the mean ± SD. HDL – high-density lipoprotein, LDL – low-density lipoprotein, VLDL – very-low-density lipoprotein, mg/dL= milligram per deciliter. P values for total cholesterol were calculated by ANOVA, while those for the other parameters were calculated by the Kruskal-Wallis test. The lowercase letters indicate significant differences detected between genotypes in the 2 X 2 comparisons, where a and b indicate significance compared to the GG and GC genotypes, respectively.