Skip to main content
. 2016 Aug 8;39(4):646–657. doi: 10.1590/1678-4685-GMB-2015-0323

Table 1. Estimated parameters under different codon substitution models for OXTR, AVPR1a, AVPR1b, and AVPR2.

Model dN/dS Estimated parameters p value
AVPR1a M7: β 0.1504 [p=0.22139, q=1.22306] -10046.63 M7 vs M8 p < 0.001
M8: β&ω 0.1399 p0=0.95125, (p2 =0.04875), ω2=1.04782 -10036.96
AVPR1b M7: β 0.1723 [p=0.33171, q=1.56124] -10988.96 M7 vs M8 p < 0.001
M8: β&ω 0.1709 p0=0.96686, (p2 =0.03314), ω2 =1.39536 -10973.98
AVPR2 M7: β 0.1123 [p=0.17525, q=1.33373] -5496.23 M7 vs M8 p = 0.04
M8: β&ω 0.1053 p0=0.96649, (p2 =0.03351), ω2 =1.00000 -5493.606
OXTR M1a: Nearly 0.0896 p0=0.93893, (p1=0.06107) -4401.07
Neutral
0=0.03039), (ω1=1.00000) M1a vs M2a p > 0.999
M2a: Selection 0.0896 p0=0.93893, p1=0.06107, (p2=0.00000) -4401.07
0=0.03039), (ω1=1.00000), ω2=36.81273

p0 = proportion of sites where ω < 1, p1 = proportion of sites where ω = 1, and p2 = proportion of sites where ω > 1 (selection models only); ω0 < 1 (negative selection), ω1 ≅ 1 (neutral or relaxing selection), and ω2 > 1 (positive selection). ℓ= Log likelihood values. Likelihood ratio tests were performed between neutral models (M1a- nearly neutral, and M7 - beta) and models that identify positive selection (M2a - selection, and M8, β&ω - beta +selection). The comparisons M1 vs M2 and M7 vs M8 had 2 degrees of freedom. Within parentheses: fixed parameters; within brackets: βparameters p and q. dN/dS = non-synonymous/synonymous rate ratio.