Table 1.
6-mo
|
24-mo
|
|||
---|---|---|---|---|
Soleus | Tibialis | Soleus | Tibialis | |
Glycogen synthase activity ratio (−G6P/+G6P) | ||||
Diet | ||||
AL | 0.24 ± 0.02 | 0.28 ± 0.02 | 0.12 ± 0.02** | 0.23 ± 0.01 |
ALF | 0.16 ± 0.01† | 0.32 ± 0.02 | 0.11 ± 0.01 | 0.23 ± 0.03* |
CR | 0.20 ± 0.03 | 0.27 ± 0.02 | 0.17 ± 0.01 | 0.27 ± 0.01 |
Glycogen phosphorylase activity ratio (−AMP/+AMP) | ||||
Diet | ||||
AL | 0.69 ± 0.08 | 0.84 ± 0.04 | 0.58 ± 0.03 | 0.66 ± 0.09 |
ALF | 0.74 ± 0.02 | 0.85 ± 0.03 | 0.65 ± 0.07 | 0.65 ± 0.06 |
CR | 0.71 ± 0.05 | 0.85 ± 0.03 | 0.59 ± 0.06 | 0.79 ± 0.15 |
Enzyme activities were assessed in extracts from SOL and TA muscles and expressed as the activity ratio. Means ± SEM from at least 5 rats in each group are shown. Age influenced: GS activity ratio (F 17.4, p < 0.001) in SOL and (F 8.40, p < 0.01) in TA and GP activity ratio (F 11.3, p < 0.005) in TA. Diet influenced: GS activity ratio (F 5.57, p < 0.01) in SOL. The significance of the differences is: versus AL within same muscle and age †p < 0.05; versus 6-mo rats comparing equivalent diet and muscle *p < 0.05 and **p < 0.001.