Figure 2.

Partial regression residual plots of methylglyoxal hydroimidazolone concentration and renal structural variables. The residuals were computed from regressing each of these variables on age, sex, diabetes duration, HbA_1c, treatment assignment, MAP, and GFR. Methylglyoxal hydroimidazolone, total filtration surface, and cortical fractional interstitial volume are shown on a log base 2 scale. Pearson partial r and the corresponding P value are shown. TFS, total filtration surface; VvInt, cortical interstitial fractional volume.