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. 2016 Nov 4;17(1):698–714. doi: 10.1080/14686996.2016.1242999

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© 2016 The Author(s). Published by National Institute for Materials Science in partnership with Taylor & Francis

This is an Open Access article distributed under the terms of the Creative Commons Attribution License CC-BYhttp://creativecommons.org/licenses/by/4.0/which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 9. — SEM images of (A, B) hBMCs with normal morphologies on planar control materials; (C) hBMC conforming to a groove edge of smaller and shallower pit (arrow); (D) hBMC with filopodia entering a small pit and inset (e) shows evidence of endogenous matrix formation; (E) filopodial guidance in larger and deeper pit (arrow); (F) filopodial guidance (arrow) and inset (e) shows evidence of endogenous matrix formation; (G, H) contact guidance of hBMC and their filopodia on narrow grooves; (I) hBMC aligning along the wide grooves (arrow) and spanning across grooves (double headed arrows); (J) filopodial guidance on the wide grooves (arrows). Images reproduced with permission from [54].