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. Author manuscript; available in PMC: 2016 Nov 29.
Published in final edited form as: Nat Rev Dis Primers. 2016 Mar 3;2:16006. doi: 10.1038/nrdp.2016.6

Figure 8. Assessment of aortic valve mineralization activity by positron emission tomography – computed tomography.

Figure 8

Coaxial short axis views of the aortic valve from one patient with aortic sclerosis, one patient with mild aortic stenosis and one patient with moderate aortic stenosis. Left panels: baseline multi-detector computed tomography (MDCT) images of the aortic valve; regions of macrocalcification appear white. Middle panels: baseline fused MDCT and 18F-sodium fluoride (NaF) positron emission tomography (PET) images showing intense 18F-NaF uptake (red yellow areas) both overlying and adjacent to existing calcium deposits on the MDCT. Right panels: One-year follow-up (without intervention) MDCT images demonstrate increased calcium accumulation in much the same distribution as the baseline PET activity. Reproduced with permission from172.