Table 2.
Parameters and criteria for the assessment of aortic stenosis severity
| Technique | Parameter | Aortic Sclerosis | Mild AS | Moderate AS | Severe AS | Very Severe AS | Low Gradient Severe AS |
|---|---|---|---|---|---|---|---|
| Doppler-echocardiography | Peak aortic jet velocity (VPeak) |
< 2 m/s | 2 – 3 m/s | 3 – 4 m/s | ≥ 4 m/s | ≥ 5 m/s | < 4 m/s |
| Mean gradient ΔPMean |
<10 mmHg | 10 – 19 mmHg | 20 – 39 mmHg | ≥ 40 mmHg | ≥ 50 mmHg | <40 mmHg | |
| Aortic Valve Area (AVA=SVLVOT/VTIAo) |
> 2.0 cm2 | 1.6 – 2.0 cm2 | 1.1 – 1.5 cm2 | ≤1.0 cm2 | ≤0.6 cm2 | ≤1.0 cm2 | |
| Indexed AVA (AVAi=AVA/BSA) |
> 1.2 cm2/m2 | 1.0 – 1.2 cm2/m2 | 0.7 – 0.9 cm2/m2 | ≤0.6 cm2/m2 | ≤0.45 cm2/m2 | ≤0.6 cm2/m2 | |
| Dobutamine stress echocardiography | Stress mean gradient | NA | NA | NA | NA | NA | ≥ 40 mmHg |
| Stress AVA | NA | NA | NA | NA | NA | ≤1.0 cm2 | |
| MDCT | Aortic valve calcification score | NA | NA | Men ≥1200 AU Women ≥700 AU |
Men ≥2000 AU Women ≥1200 AU |
NA | Men ≥2000 AU Women ≥1200 AU |
AVA, aortic valve area; AVAi, indexed AVA; BSA, body surface area; ΔPMean, mean transvalvular gradient; MDCT, multidetector computed tomography; SV, stroke volume; VPeak, peak aortic jet velocity; VTIAo, velocity-time integral of the transvalvular flow; NA, not applicable or not available.