Figure 2.

CD spectra of 10 μM dsDNA (A) and gqDNA (B) without osmolyte (continuous line), with 40wt% TMAO (broken line) or with 20wt% urea (dotted line). All measurements were carried out in the buffer containing 100 mM KCl, 10 mM K₂HPO₄, and 1 mM K₂EDTA at 25 °C.