Silencing of SETD2, SMARCC1, or PBRM1 is associated to increased cell proliferation. (A) PBRM1, SETD2, and SMARCC1 genes were efficiently silenced in PPM-Mill cells at 72 h using siRNAs. (B) At the same time point, viability of silenced cells was significantly higher than control. Data were compared using Mann–Whitney test; *P < 0.05, **P < 0.01.