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Targeted deletions of Itgb1 in the pituitary gland. (A) Pitx1-cre eliminates integrin β1 at e10.5 in Rathke’s pouch epithelium (Right, between arrows). Laminin marks basement membrane. (Scale bar: 130 μm.) Image on the left is shown again as the first panel in an ontogenic series in Fig. S1B. (B) Prop1-cre eliminates integrin β1 at e14.5 in pituitary gland epithelium (enclosed by dotted lines). (Scale bar: 130 μm.) Midsagittal sections are shown in A and B.
