Table 1.
Patient–control comparison
| Parameters | Cohen’s d | βDX ± SE (P value) | Covariates (P value) | F value (P value) |
| DKI parameters | ||||
| FA | 0.58 | −0.023 ± 0.006 (5.5⋅10−5) | Age (2.1⋅10−5) | 11.87 (3.8⋅10−7) |
| L║ | 0.23 | −4.1 ± 2.5⋅10−5 (0.09) | Age (0.001) | 3.3 (0.02) |
| L┴ | 0.43 | 7.4 ± 2.5⋅10−5 (0.03) | Age (0.009) | 7.0 (1.7⋅10−4) |
| KA | 0.57 | −0.03 ± 0.008 (2.2⋅10−4) | Age (0.05) | 6.1 (5.7⋅10−4) |
| K║ | 0.51 | −0.06 ± 0.02 (5.8⋅10−4) | None | 6.3 (4.3⋅10−4) |
| K┴ | 0.19 | −0.05 ± 0.04 (0.17) | None | 0.89 (0.4) |
| PD parameters | ||||
| Mu | 0.18 | 0.006 ± 0.005 (0.17) | None | 1.5 (0.2) |
| PDI | 0.56 | −0.005 ± 0.001 (2.6⋅10−4) | Age (0.02) | 9.7 (5.2⋅10−6) |
| Neuropsychological measurements | ||||
| Digit Symbol Substitution Test (processing speed) | 0.59 | −13.1 ± 3.5 (3⋅10−5) | Age (0.005) | 11.2 (8.7⋅10−7) |
| Digit Span (working memory) | 0.44 | −3.1 ± 1.5 (0.01) | Age (0.05) | 3.8 (0.01) |
Comparison includes effect size of diagnosis (Cohen’s d); β coefficients of the linear regression for diagnosis (DX), age, and sex; and the significance of the regression F(3,183) and P values.