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The possible endogenous mechanisms of action of repurposed drugs. The drugs and their targets are highlighted in lighter and darker shaded boxes, respectively. The anagram MAGP is used to indicate the ’mycolic acid–arabinogalactan–peptidoglycan’ layer of the mycobacterial cell wall and PBP refers to the penicillin-binding proteins responsible for the maturation of the cell wall peptidoglycan.
