Table 2. Prior antibiotic administration and clinical information of BAL samples.

BAL ID #	Reason for BAL	On ABX at time of BAL	Antibiotic administration(dose frequency)	Clinical presentation
32	Diagnostic	Yes	6 doses of 1500mg Vancomycin (every 12 hours); 9 doses 3.375g piperacillin/tazobactam (every 8 hours) prior to BAL	CXR bilateral chest infiltrate; acute respiratory failure
34	Diagnostic	No	3 doses of 200mg ciprofloxacin (daily) prior to BAL	Previous BAL 4 days prior grew 70k CFU Enterobacter cloacae; CXR Lung opacity clearing since previous BAL
42	Screening	No	One dose 600mg clindamycin 48 hour prior to BAL	No VE at time of Bal
69	Diagnostic	No	No antibiotics prior to BAL	No VE at time of BAL; subsequent BAL 3 days later had 10K CFU Staphylococcus aureus, some infiltrate on CXR at time of second BAL
70	Diagnostic	Yes	7 doses of 1750mg vancomycin (every 12 hours), last dose 5 days prior to BAL; 21 doses of 3.37g piperacillin/tazobactam (every 8 hours) for 8 days preceding BAL	ABX for positive Enterobacter urine culture; CPIS 8
133	Screening	Yes	3 doses of 600mg ciprofloxacin (daily) prior to BAL	ABX for abdominal abscess; CXR minimal lower lung infiltrates; extubated 2 days after BAL
137	Screening	Yes	7 doses of 3.375g piperacillin/tazobactam (every 8hours) 2 days prior to BAL; 2 doses 1000mg vancomycin (every 12 hours) prior to BAL	admitted to hospital 3 days prior to BAL with possible Pneumonia(cough, sputum production, tachypnea)
164	Screening	Yes	3 doses of 600mg clindamycin (every 12 hours) immediately prior to BAL	No associated Ventilator events
186	Screening	No	No antibiotics prior to BAL	Intubated for >2 weeks with no ventilator events
189	Screening	Yes	2 doses of 400mg gentamicin (daily) prior to BAL	CXR clear at time of BAL
196	Diagnostic	No	No antibiotics prior to BAL	No associated Ventilator events; extubated 2 days after BAL
197	Screening	Yes	24 doses of 3.375g piperacillin/tazobactam (every 8 hours) completed 13 days before BAL; 39 doses 500mg metronidazole (3x per day) immediately prior to BAL; 7 doses of 1250mg vancomycin (every 12 hr) immediately prior to BAL; one doses 100mg micafungin 24hr prior to BAL	No associated Ventilator events; extubated 2 days after BAL
201	Screening	Yes	6 doses piperacillin/tazobactam (every 8 hours) prior to BAL; one dose 500mg azithroymycin 48 hours prior to BAL; one dose 1500mg Vancomycin 24 hours prior to BAL	No associated Ventilator events
208	Screening	No	One dose 120mg gentamycin 120mg 5 days prior to BAL; 7 doses of 80mg gentamycin (daily) last dose 2 days before BAL	No associated Ventilator events
209	Screening	Yes	2 doses of 400mg flucanozole (every 24 hrs) immediately before BAL; one dose 80mg gentamycin 3 days before BAL; 7 doses of 3.375g piperacillin/tazobactam (every 8 hours) immediately before BAL	No significant symptoms at time of BAL; subsequent CXR showed increasing infiltrate and edema; Positive Pseudomonas infection in subsequent BALs(4 days-40kCFU and 9 days-100kCFU after initial BAL)