Table 1. Screening Yield and Number Needed to Screen among household contacts and Close community contacts of index patients in intervention* districts**, Pakistan.
Contacts screening | Index household | Close community within 50m | Total |
---|---|---|---|
radius of index HH | |||
Total screened | 89222 | 693821 | 783043 |
Presumptive TB patients | 5173 (5.8%) | 18568 (2.7%) | 23741 (3.0%) |
Investigated for sputum smear | 3356/5173 (64.9%) | 11617/18568 (62.6%) | 14973/23741 (63.1%) |
microscopy | |||
Number smear positive | 932 /3356 (27.8%) | 2977/ 11617 (25.6%) | 3909/14973 (26.1%) |
Number smear negative eligible | 2424/3356 (72.2%) | 8640/ 11617 (74.4%) | 11064/14973 (73.9%) |
for Xpert testing | |||
Number tested using Xpert | 1476/2424 (60.9%) | 5401/8640 (62.5%) | 6877/11064 (62.2%) |
Number of TB positive on Xpert | 160/1476 (10.8%) | 362/5401 (6.7%) | 522/6877 (7.6%) |
Number of Rifampicin Resistant | 14/160 (8.8%) | 30/362 (8.3%) | 44/522 (8.4%) |
positive | |||
Number who underwent Chest | 992/5173 (19.2%) | 4027/18568 (21.7%) | 5019/23741 (21.1%) |
X-ray | |||
Number clinically diagnosed as | 133/992 (13.4%) | 426/4027 (10.6%) | 559/5019 (11.1%) |
TB based on Chest X-ray | |||
Bacteriologically confirmed | 996/5173 (19.3%) | 3088/18568 (16.6%) | 4084/23741 (17.2%) |
TB | |||
NNS among total screened | 90 | 225 | 192 |
NNS among presumptive TB | 5 | 6 | 5.8 |
All forms of TB | 1154/5173 (22.3%) | 3556/18568 (19.1%) | 4710/23741 (19.8%) |
• Lahore | 479 (41.5) | 1540 (43.3) | 2019 (42.9) |
• Faisalabad | 363 (31.5) | 1279 (36.0) | 1642 (34.9) |
• Rawalpindi | 277 (24.0) | 668 (18.8) | 945 (20.0) |
• Islamabad | 35 (3.0) | 69 (1.9) | 104 (2.2) |
NNS among total screened | 77 | 195 | 166 |
NNS among presumptive TB | 5 | 5 | 5.0 |
Treatment initiated | 1126 (97.6%) | 3478 (97.8%) | 4604 (97.7%) |
Child TB patients among child | 84/1269 (6.6%) | 213/4596 (4.6%) | 297/5865 (5.1%) |
presumptive | |||
NNS among total child screened | 358 | 1143 | 921 |
NNS among presumptive child | 15 | 22 | 20 |
TB patients |
*Community screening in addition to household screening within 50 meter radius of index house
** Lahore, Faisalabad, Rawalpindi and Islamabad