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. 2016 Nov 29;11(11):e0165813. doi: 10.1371/journal.pone.0165813

Table 1. Screening Yield and Number Needed to Screen among household contacts and Close community contacts of index patients in intervention* districts**, Pakistan.

Contacts screening Index household Close community within 50m Total
radius of index HH
Total screened 89222 693821 783043
Presumptive TB patients 5173 (5.8%) 18568 (2.7%) 23741 (3.0%)
Investigated for sputum smear 3356/5173 (64.9%) 11617/18568 (62.6%) 14973/23741 (63.1%)
microscopy
Number smear positive 932 /3356 (27.8%) 2977/ 11617 (25.6%) 3909/14973 (26.1%)
Number smear negative eligible 2424/3356 (72.2%) 8640/ 11617 (74.4%) 11064/14973 (73.9%)
for Xpert testing
Number tested using Xpert 1476/2424 (60.9%) 5401/8640 (62.5%) 6877/11064 (62.2%)
Number of TB positive on Xpert 160/1476 (10.8%) 362/5401 (6.7%) 522/6877 (7.6%)
Number of Rifampicin Resistant 14/160 (8.8%) 30/362 (8.3%) 44/522 (8.4%)
positive
Number who underwent Chest 992/5173 (19.2%) 4027/18568 (21.7%) 5019/23741 (21.1%)
X-ray
Number clinically diagnosed as 133/992 (13.4%) 426/4027 (10.6%) 559/5019 (11.1%)
TB based on Chest X-ray
Bacteriologically confirmed 996/5173 (19.3%) 3088/18568 (16.6%) 4084/23741 (17.2%)
TB
NNS among total screened 90 225 192
NNS among presumptive TB 5 6 5.8
All forms of TB 1154/5173 (22.3%) 3556/18568 (19.1%) 4710/23741 (19.8%)
  • Lahore 479 (41.5) 1540 (43.3) 2019 (42.9)
  • Faisalabad 363 (31.5) 1279 (36.0) 1642 (34.9)
  • Rawalpindi 277 (24.0) 668 (18.8) 945 (20.0)
  • Islamabad 35 (3.0) 69 (1.9) 104 (2.2)
NNS among total screened 77 195 166
NNS among presumptive TB 5 5 5.0
Treatment initiated 1126 (97.6%) 3478 (97.8%) 4604 (97.7%)
Child TB patients among child 84/1269 (6.6%) 213/4596 (4.6%) 297/5865 (5.1%)
presumptive
NNS among total child screened 358 1143 921
NNS among presumptive child 15 22 20
TB patients

*Community screening in addition to household screening within 50 meter radius of index house

** Lahore, Faisalabad, Rawalpindi and Islamabad