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. 2016 Nov 29;13(11):e1002188. doi: 10.1371/journal.pmed.1002188

Table 5. Multivariable regression of LTL on all biomarkers, age 20–84, NHANES 1999–2002.

Model 1—unadjusted Model 2—demographic adjusted
coef 95% CI coef 95% CI
Lipoproteins
HDL cholesterol -0.0284 -0.0676, 0.0108 0.0158 -0.0224, 0.054
LDL cholesterol -0.00285 -0.024, 0.0183 0.00938 -0.00903, 0.0278
Triglycerides -0.0505* -0.0902, -0.0107 -0.0194 -0.055, 0.0163
Blood sugar
Glucose -0.013 -0.0721, 0.0462 0.0271 -0.0305, 0.0846
Insulin resistance 0.0414* -0.0142, 0.097 0.0101 -0.039, 0.0593
HbA1c -0.0277 -0.0913, 0.0359 -0.0172 -0.0796, 0.0452
Circulatory pressure
Systolic blood pressure -0.0789* -0.119, -0.0385 0.00514 -0.0291, 0.0394
Diastolic blood pressure 0.0336* 0.00886, 0.0584 -0.0143 -0.0417, 0.013
Pulse rate -0.015 -0.0384, 0.00827 -0.0314 -0.0557, -0.00706
Proinflammatory
C-reactive protein -0.0138 -0.0663, 0.0387 -0.0286 -0.0781, 0.021
Fibrinogin -0.0158 -0.0627, 0.031 0.015 -0.0313, 0.0612
Kidney function
Cystatin C -0.0292** -0.0483, -0.0101 -0.0136 -0.0377, 0.0105
Glomerular filtration rate 0.123 0.0858, 0.16 -0.00206 -0.0465, 0.0424
Albumin: Creatinine 0.0434 -0.0159, 0.103 0.0119 -0.0451, 0.069
Adiposity
BMI 0.0705 0.00938, 0.132 -0.0417 -0.108, 0.0241
waist circumference -0.0809* -0.147, -0.0147 0.0306 -0.0359, 0.0971
% body fat -0.0415 -0.0763, -0.0067 -0.00753 -0.0477, 0.0327

The effective sample size for each of the models was 3,407 because of the use of fasting sample weights. Model 1 includes only the 17 biomarkers shown in the table. Model 2 additionally adjusts for the following covariables: race/ethnicity (white, Mexican American, black, and other), gender, foreign birthplace, education (less than high school, high school diploma, more than high school), class of work (white collar high, blue collar high, white collar low, blue collar low, no work), income, marital status (married or living with partner), age (as continuous), and age-squared.