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. 2016 Nov 29;11(11):e0167250. doi: 10.1371/journal.pone.0167250

Fig 3. Total IgM but not NTHi-specific IgM are increased in the serum of NTHi+ve patients.

Fig 3

Total IgM in (A) serum or (C) BAL was analysed by MSD multiplex assay. (B) Serum IgM or (D) BAL IgM specific for NTHi was assessed by flow cytometry. Open circles indicate NTHi-ve COPD patients, closed circles indicate NTHi+ve patients. Bars represent median values and each dot represents an individual volunteer. n = 8 for controls, n = 17 for NTHi-ve and n = 7 for NTHi+ve patients. Data were analysed using a Kruskal-Wallis ANOVA followed by a Dunn’s post hoc test. * p<0.05, *** p<0.01