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. Author manuscript; available in PMC: 2016 Nov 29.
Published in final edited form as: Curr Alzheimer Res. 2015;12(7):648–654. doi: 10.2174/1567205011666141107153634

Table 2.

Racial differences in brain structural measures and cognitive test scores.

White (n =168) Black (n =115) P Valuec
Brain structural measures:
White matter hyperintensities a, median (IQR) 0.0032 (0.0010, 0.0067)e 0.0041 (0.0011, 0.0124) 0.062
Gray matter atrophy b, mean (SD) 0.72 (0.021) 0.72 (0.025) 0.4
Mean diffusivity, mm2s−1, mean (SD) 1.32 (0.106) 1.28 (0.114) 0.032
Cognitive tests:
Digit symbol substitution test (DSST), points, mean (SD) 40 (12.56) 32 (13.49) 0.001
Modified mini--mental score (3MS), median (IQR), points 96 (93, 98) 91.5 (86, 96) 0.006

Abbreviations: IQR=inter--quartile range; SD=standard deviation

a

White matter hyperintensities: total volume of white matter hyperintensities/total brain volume.

b

Gray matter atrophy: (intracranial volume--gray matter volume)/intracranial volume.

c

p--Values were calculated from linear regression models adjusted for sex, literacy, drinking, income, diabetes, body mass index.