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A. SERCA uptake velocity measured by 45Ca SERCA uptake assay (control n=6, MYBPC3-mutation HCM n=7, MYH7-mutation HCM n=3, sarcomere-negative HCM n=5). B. Normalized SERCA uptake velocity. C. Total SERCA uptake measured by 45Ca SERCA uptake assay as maximum (saturating) uptake after one hour incubation. D. Normalized total SERCA uptake measured by 45Ca SERCA uptake assay as maximum (saturating) uptake after one hour incubation. *p<0.05 for all HCM groups vs control.
