Table 1.
Age (y) | % male |
Septal thickness (mm) |
EF (%) | LVOT gradient (mmHg) |
|
---|---|---|---|---|---|
Controls (n=8) | 56 ± 6 | 13 | 11.6 ± 0.8 | 64 ± 2 | - |
HCM patients | |||||
No sarcomere mutation (n=10) | 49 ± 3 | 80 | 20.4 ± 0.9* | 67 ± 2 | 73 ± 18 |
MYH7 mutations (n=8) | 44 ± 6 | 50 | 18.3 ± 0.8 | 73 ± 4* | 68 ± 8 |
MYBPC3 mutations (n=17) | 39 ± 3* | 41 | 28.0 ± 3.3* | 75 ± 2*† | 77 ± 11 |
Overall P-value | 0.038 | <0.001 | 0.006 | 0.9 |
P<0.05 vs controls
P<0.05 vs HCM patients with no sarcomere mutation