Table 3.

GO enrichment of protein families disappeared uniformly in all nematodes (free-living nematode specific families having born time before the split of Trichinella spiralis).

GO Category	GO terms	GO descriptor	Under-represent P value	Over-represent P value
Biological processes
	GO:0000186	activation of MAPKK activity	1.00E + 00	2.45E − 02
	GO:0002119	nematode larval development	2.90E − 02	9.83E − 01
	GO:0006303	double-strand break repair via non-homologous end joining	9.99E − 01	4.85E − 02
	GO:0006412	translation	1.74E − 02	1.00E + 00
	GO:0007186	G-protein coupled receptor protein signaling pathway	9.99E − 01	4.96E − 03
	GO:0007218	neuropeptide signaling pathway	9.99E − 01	1.92E − 02
	GO:0009792	embryonic development ending in birth or egg hatching	2.28E − 03	9.99E − 01
	GO:0040017	positive regulation of locomotion	3.40E − 02	1.00E + 00
	GO:0048268	clathrin coat assembly	9.99E − 01	4.85E − 02
Molecular function
	GO:0001584	rhodopsin-like receptor activity	9.96E − 01	1.69E − 02
	GO:0003707	steroid hormone receptor activity	1.00E + 00	5.07E − 04
	GO:0003735	structural constituent of ribosome	4.83E − 02	1.00E + 00
	GO:0003993	acid phosphatase activity	9.99E − 01	1.64E − 02
	GO:0004190	aspartic-type endopeptidase activity	1.00E + 00	3.39E − 03
	GO:0004497	monooxygenase activity	9.98E − 01	1.79E − 02
	GO:0004792	thiosulfate sulfurtransferase activity	9.99E − 01	4.47E − 02
	GO:0004930	G-protein coupled receptor activity	9.98E − 01	2.88E − 02
	GO:0005158	insulin receptor binding	9.99E − 01	4.47E − 02
	GO:0005506	iron ion binding	9.96E − 01	1.79E − 02
	GO:0005545	phosphatidylinositol binding	9.99E − 01	4.47E − 02
	GO:0008191	metalloendopeptidase inhibitor activity	9.99E − 01	4.47E − 02
	GO:0008825	cyclopropane-fatty-acyl-phospholipid synthase activity	1.00E + 00	2.26E − 02
	GO:0009055	electron carrier activity	9.99E − 01	3.99E − 03
	GO:0020037	heme binding	9.98E − 01	1.16E − 02
	GO:0045296	cadherin binding	9.99E − 01	4.47E − 02
	GO:0051015	actin filament binding	1.00E + 00	9.87E − 03