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. 2016 Nov 30;6:173. doi: 10.3389/fcimb.2016.00173

Figure 2.

Figure 2

Inhibition of pathogen attachment to corneal epithelial cells by the presence of different GAGs. (A) Adhesion of Staphyloccocus aureus (1), Staphyloccocus epidermidis (2), Streptoccocus pyogenes (3), Streptococcus pneumoniae (4), Escherichia coli (5), Klebsiella pneumoniae (6), Serratia marcescens (7), Neisseria gonorrhoeae (8), Pseudomonas aeruginosa (9), and Haemophilus influenzae (10) in the presence of different concentrations of HS (●), CS A (□), CS B (■), CS C (▲), and a mixture of all GAGs (○). (B) Comparative effect of the different individual GAG species and the mixture of them all on bacterial adherence to corneal cells. (C) Comparative effect of the different GAG species and the mixture on adherence of Gram-positive (●) and Gram-negative (○) bacteria. (D) Comparative effect of the different individual GAG species and the mixture (40 nM) on bacterial adherence to ECM. The spreads represent the standard deviations. Statistically significant differences are denoted by ***, **, and *, which indicate p < 0.001, p < 0.01, and p < 0.05, respectively and n.s. indicates that differences were not significant.