Figure 4.
Effect of peptides with heparin binding sequences on pathogen attachment to corneal epithelial cells. (A) Effect of peptide QKKFKN on adherence of S. aureus (●) and P. aeruginosa (○), and effect of peptide FKKKYGKS on adherence of S. aureus (▲) and P. aeruginosa (Δ). (B) Effect on pathogen attachment to corneal epithelial cells; gray bars: QKKFKN 20 nM; black bars: FKKKYGKS 20 nM. (C) Adherence differences of Gram-positive (●) and Gram-negative (○) bacteria in the presence of the short or the long peptide. Statistically significant differences are denoted by ***, which indicate p < 0.001. n.s., not significant.