Fig. 1.

Efficiency of CD40 expression silencing with the siCD40. (A). Dot plot of CD40 expression in the aortas of ApoE^−/− mice at basal conditions (B/8w), or treated with the anti-CD40 siRNA (siCD40) or with the SC control siRNA (SC). Mean is represented by a line. (B). Box plot quantifying CD40⁺ cells in ascending aortas of mice treated with siCD40 (n=12 mice) or SC (n=7). (C). Representative staining of CD40⁺ cells in the aortic sinus (arrows). Scale bars are 100 µm. Kruskall–Wallis test.