Table 3.
Fold change in expression of genes in the study groups compared to KHI and their statistical significance as per one-way ANOVA followed by post hoc Tukey analysis.
| Gene | Fold change compared to KHI group |
Statistical significance, p |
|---|---|---|
| G6PD∗ | CKDu, 0.73 | 0.703 |
| N = 75 | CKD, 0.62 | 0.562 |
| O = 1 | GH, 0.42 | 0.137 |
|
| ||
| GSTM1 | CKDu, 2.60 | 0.036 |
| N = 53 | CKD, 1.58 | 0.729 |
| NE = 25 | GH, 2.37 | 0.177 |
| O = 4 | ||
|
| ||
| GCLC | CKDu, 3.16 | 0.001 |
| N = 74 | CKD, 4.10 | 0.002 |
| NE = 1 | GH, 7.27 | 0.000 |
| O = 7 | ||
|
| ||
| NLRP3∗ | CKDu, 6.55 | 0.006 |
| N = 54 | CKD, 11.30 | 0.010 |
| NE = 3 | GH, 2.38 | 0.553 |
|
| ||
| FGF23∗ | CKDu, 21.94 | 0.003 |
| N = 49 | CKD, 134.97 | 0.001 |
| NE = 6 | GH, 2.52 | 0.904 |
N: number included for one-way ANOVA
O: outliers
NE: number of samples not expressing gene
∗total sample less than 82 due to insufficient sample amount.