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. 2016 Nov 30;6:38248. doi: 10.1038/srep38248

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Copyright © 2016, The Author(s)

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The circles from the innermost to the outermost: Circle 1 for GC skew (G−C)/(G+C); Circle 2 for GC content; Circle 3 for rRNA and tRNA; Circles 4 and 5 for protein coding genes in the reverse and forward strands respectively; Circles 6 and 7 for N4-methylcytosine (m4C) and N6-methyladenosine (m6A) sites in CDS/rRNA/tRNA in the reverse and forward strands respectively; and Circle 8 for m4C and m6A sites in intergene regions.