Table 2.

Sensitivity, specificity, PPV and NPV of the GDRS according to selected cut-offs of predicted 5-year diabetes risk in the ‘GNHIES98—longitudinal sample’ (N=3625) and the ‘DEGS1—cross-sectional sample’ (N=6048)

Predicted 5-year diabetes risk (%)	GDRS points* (≈)	GNHIES98—longitudinal sample				DEGS1—cross-sectional sample
		Prediction of incident diagnosed type 2 diabetes				Detection of prevalent undiagnosed diabetes
		Sensitivity	Specificity	PPV	NPV	Sensitivity	Specificity	PPV	NPV
1.0	480	0.97	0.49	0.04	1.00	0.95	0.50	0.04	1.00
2.0	550	0.96	0.64	0.06	1.00	0.91	0.63	0.05	1.00
2.5	572	0.96	0.69	0.06	1.00	0.89	0.67	0.05	1.00
3.0	590	0.95	0.72	0.07	1.00	0.88	0.70	0.06	1.00
4.0	619	0.84	0.78	0.08	1.00	0.81	0.75	0.07	0.99
5.0	641	0.75	0.81	0.08	0.99	0.78	0.79	0.07	0.99
10.0	711	0.51	0.91	0.12	0.99	0.61	0.89	0.11	0.99
15.0	751	0.27	0.95	0.10	0.98	0.44	0.93	0.13	0.99
20.0	780	0.20	0.97	0.12	0.98	0.36	0.96	0.14	0.99

*In the ‘GNHIES98—longitudinal sample’, GDRS points ranged from 115.4 to 1000.5 points. In the ‘DEGS1—cross-sectional sample’, GDRS points ranged from 77.3 to 1128.2 points.

DEGS1, German Health Interview and Examination Survey for Adults; GDRS, German Diabetes Risk Score; GNHIES98, German National Health Interview and Examination Survey 1998; NPV, negative predictive value; PPV, positive predictive value.