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. 2016 Nov 30;6:38089. doi: 10.1038/srep38089

Table 4. Association of smoking and alcohol consumption with prevalence of MS.

  Men   Women
Percentages of Case (%) OR (95% CI)a OR (95% CI)b Percentages of Case (%) OR (95% CI)a OR (95% CI)b
Smoking status
 Never 21.89 1.0 1.0   25.72 1.0 1.0
 Former 19.23 1.00 (0.88−1.13) 1.14 (0.97−1.35)   28.80 1.06 (0.85−1.33) 1.32 (1.00−1.73)
 Current 25.48 1.16 (0.89−1.52) 1.24 (0.89−1.72)   32.84 1.49 (0.83−2.67) 2.39 (1.22−4.67)
p for trend   0.5284 0.0669     0.2307 0.0022
Smoking rate (cigars per day)
 Never 21.89 1.0 1.0 Never 25.71 1.0 1.0
 ≤10 17.04 0.87 (0.74−1.03) 1.01 (0.82−1.24) ≤5 27.84 1.02 (0.71−1.46) 1.21 (0.79−1.84)
 ≤20 21.37 1.12 (0.96−1.32) 1.15 (0.94−1.41) ≤10 29.15 1.06 (0.75−1.49) 1.34 (0.91−2.08)
 >20 24.73 1.04 (0.70−1.55) 0.98 (0.60−1.62) >10 35.29 1.53 (0.95−2.46) 1.96 (1.12−3.43)
p for trend   0.3261 0.1535     0.1576 0.0046
Years of smoke
 Never 21.91 1.0 1.0   25.72 1.0 1.0
 ≤25 17.35 0.90 (0.73−1.11) 1.01 (0.79−1.30)   24.69 0.81 (0.52−1.21) 0.85 (0.53−1.40)
 >25 20.05 1.01 (0.88−1.17) 1.11 (0.93−1.33)   31.53 1.26 (0.96−1.64) 1.74 (1.26−2.40)
p for trend   0.8818 0.2086     0.2067 0.0028
Ever drink  
 Never 21.61 1.0 1.0   26.28 1.0 1.0
 Ever 20.39 0.91 (0.81−1.03) 0.89 (0.76−1.04)   22.17 0.68 (0.59−0.78) 0.70 (0.69−0.82)
Beer: months of drink
 0 22.75 1.0 1.0   26.15 1.0 1.0
 ≤3 17.04 0.75 (0.64−0.87) 0.94 (0.79−1.12)   22.76 0.77 (0.63−0.93) 0.87 (0.70−1.07)
 >3 17.72 0.68 (0.55−0.85) 0.73 (0.56−0.94)   19.79 0.57 (0.41−0.79) 0.61 (0.42−0.88)
p for trend   <0.0001 0.0228     <0.0001 0.0050
Alcohol from beer (g/d)
 0 22.76 1.0 1.0 0 26.15 1.0 1.0
 ≤6.2 16.47 0.67 (0.57−0.80) 0.83 (0.68−1.01) ≤2.8 21.14 0.61 (0.46−0.82) 0.70 (0.51−0.97)
 ≤12.3 19.57 0.87 (0.62−1.23) 1.09 (0.74−1.59) ≤6.2 22.75 0.78 (0.62−0.99) 0.88 (0.68−1.13)
 >12.3 17.57 0.77 (0.63−0.95) 0.88 (0.70−1.12) >6.2 20.98 0.70 (0.48−1.02) 0.74 (0.49−1.13)
p for trend   0.0008 0.2737     0.0005 0.0312
Liquor: months of drink
 0 20.03 1.0 1.0   25.84 1.0 1.0
 ≤6 18.00 0.88 (0.73−1.05) 0.92 (0.74−1.14)   25.83 0.85 (0.64−1.13) 0.94 (0.68−1.30)
 >6 29.98 1.44 (1.23−1.70) 1.11 (0.87−1.42)   27.53 0.91 (0.62−1.31) 0.76 (0.47−1.23)
p for trend   0.0009 0.6774     0.2973 0.2574
Alcohol from liquor (g/d)
 0 20.13 1.0 1.0 0 25.86 1.0 1.0
 ≤12.3 19.87 0.89 (0.60−1.13) 0.85 (0.64−1.14) ≤6.2 26.46 0.88 (0.61−1.27) 1.01 (0.67−1.54)
 ≤37 22.30 1.09 (0.89−1.32) 1.02 (0.80−1.30) ≤24.6 22.50 0.64 (0.40−1.02) 0.67 (0.40−1.14)
 >37 27.68 1.35 (1.10−1.65) 1.08 (0.81−1.43) >24.6 26.99 0.92 (0.62−1.36) 0.86 (0.53−1.40)
p for trend   0.0099 0.7096     0.1457 0.2280
Rice wine: months of drink
 0 23.26 1.0 1.0   26.27 1.0 1.0
 ≤6 16.46 0.68 (0.58−0.81) 0.85 (0.70−1.04)   21.40 0.60 (0.48−0.75) 0.68 (0.53−0.86)
 >6 14.34 0.59 (0.48−0.73) 0.73 (0.58−0.93)   17.72 0.55 (0.42−0.74) 0.54 (0.39−0.75)
p for trend   <0.0001 0.0048     <0.0001 <0.0001
Alcohol from rice wine (g/d)
 0 23.26 1.0 1.0 0 26.27 1.0 1.0
 ≤8.6 15.74 0.61 (0.49−0.76) 0.80 (0.63−1.03) ≤4.1 21.54 0.61 (0.46−0.83) 0.77 (0.56−1.05)
 ≤25.7 15.34 0.67 (0.55−0.82) 0.83 (0.67−1.04) ≤12.8 18.65 0.52 (0.38−0.71) 0.49 (0.35−0.70)
 >25.7 15.81 0.65 (0.51−0.84) 0.76 (0.57−1.00) >12.8 19.35 0.61 (0.45−0.81) 0.63 (0.45−0.87)
p for trend   <0.0001 0.0152     <0.0001 <0.0001
All source of alcohol (g/d)
 0 21.91 1.0 1.0 0 26.31 1.0 1.0
 ≤16.4 20.23 0.89 (0.74−1.05) 0.97 (0.79−1.20) ≤5.6 22.31 0.66 (0.52−0.84) 0.73 (0.56−0.96)
 ≤45.2 18.43 0.79 (0.67−0.94) 0.78 (0.63−0.97) ≤18.5 21.06 0.64 (0.50−0.81) 0.67 (0.52−0.87)
 >45.2 21.54 0.97 (0.82−1.15) 0.92 (0.73−1.16) >18.5 22.33 0.69 (0.55−0.88) 0.68 (0.51−0.89)
p for trend   0.1619 0.1194     <0.0001 <0.0001

aAdjusted for age at interview and BMI.

bAdjusted for age at interview, BMI, education, marital status, occupation, exercise, risk scores of familial history, and mutually adjusted for ever smoker and ever drinker; p for trend was calculated by entering the ordinal exposure as continuous parameters in the model.