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. 2016 Nov 30;6:38116. doi: 10.1038/srep38116

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Copyright © 2016, The Author(s)

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Voltage dependence of inhibition of nAChRs by PhTX-343 (A,B) and PhTX-12 (C,D) for peak (A,C) and late (B,D) current. The bars show IC₅₀ (μM) at V_H of −60, −80 and −100 mV. ^*(p < 0.05), ^**(p < 0.01), ^***(p < 0.001) and ^***(p < 0.0001) indicate significant differences in the IC₅₀ values for −60 and −100 mV (NS = not significantly different; p > 0.05).