Table 3. ACh EC₅₀ values in the absence and presence of PhTX-343 or PhTX-12.

	[PhTX-343]	ACh EC50 (95% CI), μM
		Control		+PhTX-343
α4β2	1 μM	13	(8.9–20)	22	(5.6–89)
α4β4	1 μM	17	(8.4–36)	14	(7.8–25)
α3β4	1 μM	78	(67–91)	89	(38–207)
α3β2	1 μM	16	(12–20)	13	(9.4–18)
α7	30 μM	245	(198–304)	388*	(265–568)
α1β1γδ	10 μM	25	(18–35)	54*	(37–80)
	[PhTX-12]	Control		+PhTX-12
α3β4	10 μM	141	(113–175)	545****	(331–897)
α1β1γδ	10 μM	17	(15–20)	91****	(48–170)

ACh EC₅₀ values estimated from peak current concentration-response curves in the absence and presence of PhTX-343 or PhTX-12 shown in Figs 6 and 7. ^*p < 0.05 and ^****p < 0.0001 when compared to the EC₅₀ in the absence of toxin by an extra sum of squares F-test.