. 2016 Nov 30;6:38058. doi: 10.1038/srep38058

Table 2. Offsets between the planned and actual target and entry points of the electrode trajectories determined from (a) segmentation of its trace in post-operative MRI, (b) a 3D reconstruction of the trajectory, (c) histology.

	T/E_mri – T/E_plan mean ± s.d. (in mm)
	AP	ML	DV	ED
(a) MRI
Target (T)	−0.50 ± 0.56**	0.21 ± 0.47*	−0.78 ± 0.61***	1.24 ± 0.50
Entry (E)	−0.67 ± 0.38***	0.13 ± 0.61*	−0.27 ± 0.16***	0.92 ± 0.47
	β_mri – β_plan°	α_mri – α_plan°	β_mri – β_plan°(max)	α_mri – α_plan°(max)
Angle	1.80 ± 3.94°*	1.76 ± 4.35°	12.20°	14.43°
(b) Reconstructed
	T/E_rec-mri – T/E_plan mean ± s.d. (in mm)
	AP	ML	DV	ED
Target (T)	−0.52 ± 0.51***	0.28 ± 0.42*	0.0 ± 0.0	0.76 ± 0.44
Entry (E)	−0.69 ± 0.38***	0.14 ± 0.61*	0.0 ± 0.0	0.87 ± 0.49
	β_rec-mri – β_plan°	α_rec-mri – α_plan°	β_rec-mri–β_plan°(max)	α_rec-mri–α_plan°(max)
Angle	1.77 ± 3.69°*	1.25 ± 3.95°	9.49°	13.21°
(c) Histology
	T_hist – T_plan mean ± s.d. (in mm)
	AP	ML	DV	ED
Target (T)	−0.42 ± 0.30***	-0.12 ± 0.39	−0.36 ± 0.72	0.92 ± 0.44
Offset at target (T) – p value
	ΔT_mri vs. ΔT_rec-mri	ΔT_mri vs. ΔT_hist	ΔT_rec vs. ΔT_hist
AP	0.93	0.63	0.53
ML	0.66	0.04	0.01
DV	0.00	0.08	0.05

See the text for methodological details. T target; E entry. AP anterior-posterior, ML medial-lateral, DV dorsal-ventral, ED Euclidean distance. ***p < 0.001; **p < 0.005; *p < 0.05.