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. 2016 Nov 30;6:38060. doi: 10.1038/srep38060

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Time-lapse images of tumor spheres treated with virus-loaded HOZOT-401/F35 cells. (b) Phase-contrast and fluorescence images of tumor spheres from SW620 cells after treatment with mock, virus-free HOZOT cells, or virus-loaded HOZOT-401/F35 cells (left). Scale bars: 500 μm. Tumor size (diameter) was calculated for each group of tumor spheres treated with mock (n = 29), virus-free HOZOT cells (n = 30), or virus-loaded HOZOT-401/F35 cells (n = 18) (right). Data are expressed as mean values ± SD. *P < 0.05. N.S., not significant.