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. 2016 Nov 21;6(11):e012527. doi: 10.1136/bmjopen-2016-012527

Table 5.

Annual direct per capita costs related to severity or treatment of diabetes

Direct costs*
Ratio† 95% CI
No diabetes Reference
Cardiovascular complications
 Type 2 diabetes without cardiovascular complications 1.54‡ (1.30 to 1.82)
 Type 2 diabetes with cardiovascular complications 2.77‡ (2.12 to 3.61)
Type of treatment
 Type 2 diabetes without pharmacological treatment 1.26 (0.93 to 1.72)
 Type 2 diabetes with OAD only 1.53‡ (1.25 to 1.88)
 Type 2 diabetes with OAD and insulin 2.58‡ (1.90 to 3.50)
 Type 2 diabetes with insulin only 3.98‡ (2.74 to 5.77)
Glycaemic control
 Type 2 diabetes with HbA1c<6.5% 1.87‡ (1.51 to 2.32)
 Type 2 diabetes with 6.5%≤HbA1c<7.5% 1.64‡ (1.33 to 2.03)
 Type 2 diabetes with 7.5%≤HbA1c<9.0% 1.94‡ (1.44 to 2.62)
 Type 2 diabetes with HbA1c≥9.0% 2.24‡ (1.34 to 3.73)
Diabetes duration
 Type 2 diabetes: 0–2 years 1.90‡ (1.24 to 2.62)
 Type 2 diabetes: 3–10 years 1.44‡ (1.19 to 1.74)
 Type 2 diabetes: 11–19 years 2.21‡ (1.58 to 3.10)
 Type 2 diabetes:≥20 years 3.02‡ (2.17 to 4.22)

GEE models with a γ distribution and a log link. Models based on 9160 observations from 6803 participants.

Models are adjusted for age, sex and educational level and accounted for the repeated measurement structure.

*€ was assigned to observations with zero costs.

†Exponentiated estimate, non-diabetic participants as reference group.

‡Significant at the level of 1%.

OAD, oral antidiabetic drugs.